Scientists expose protein responsible for allergic diseases

Scientists expose protein responsible for allergic diseases Scientists at VIB-UGent have managed to unravel the functioning of what is thought to be the ‘master protein’ that drives a range of widespread allergic diseases, such as asthma and eczema. On a molecular level, the team described how a protein called TSLP assembles with its molecular partners at the surface of cells. This is the cornerstone of TSLP’s bioactivity. These insights, published in the leading scientific journal Nature Communications, also enabled the team to develop a new molecule that can block TSLP’s activity. Due to the molecule’s promise in terms of the development of new therapies for widespread allergic conditions, the researchers are currently planning follow-up studies and seeking industrial partnerships. See http://ift.tt/2nrn7bv